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SV won the bid to become Manager in a competitive selection process held in 2015. SV Health Investors (SV) SV Health Investors, formerly SV Life Sciences, is a leading healthcare and life sciences venture capital and growth equity firm.About the NFL Players Association The National Football League Players Association is the union for professional football players in the National Football League.Established in 1956, the NFLPA has a long history of assuring proper recognition and representation of players’ interests.Since its launch in October 2015, the DDF has made significant progress building an initial portfolio of 12 investments in drug discovery companies and projects predominantly in the UK and US in areas including microglial biology and inflammation, mitochondrial dynamics, trafficking and membrane biology and synaptic physiology and function.The DDF team believes there is a significant opportunity to develop dementia drugs targeting biological pathways beyond the prevailing amyloid beta hypothesis and to apply insights from areas such as oncology and immunology to develop novel drugs targeting these other biological pathways that may drive different forms of dementia.SV’s goal is to transform healthcare – one investment at a time – by supporting the entrepreneurs who create and build breakthrough companies and treatments.
sessions in New York and Cambridge, MA, where there will be opportunities for academics and innovative new companies to meet with the DDF team.
Every year, an estimated 42,000 people suffer a mild traumatic brain injury (TBI) or concussion.
Chronic traumatic encephalopathy (CTE), which results from the long term, irreversible consequences of repeated mild head impacts, is a progressive disorder with now well characterised neuropathology.
Kate Bingham, Managing Partner of SV, said: “This investment from the NFLPA is a further recognition of the potential of our approach to lead to important treatments for dementia, and, potentially, a broad range of associated neurodegenerative disorders.
At the DDF, we are focusing our efforts on scientific approaches, such as inflammation, mitochondrial function and the preservation and enhancement of healthy brain cells, and these areas are highly likely to be important to CTE or TBI, leading to renewed hope for treatment of these terrible disorders.” Ahmad Nassar, President of NFL Players, Inc.
Two years on, the DDF has made significant strides towards achieving that, attracting global investment and some of the most impressive teams, companies and entrepreneurs working in neurodegeneration research.